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| カタログ番号 | HP521026 |
|---|---|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | RG-7258 |
| 発現システム | Mammalian cells |
| ターゲット | Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR, Thymic stromal lymphopoietin protein receptor, TSLP receptor, CRLF2, CRL2, ILXR, TSLPR |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q9HC73 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | RG-7258, RG7258, RG7258 |
| 背景 | Cytokine receptor-like factor 2 (TSLPR/CRLF2) is a ~42 kDa protein. Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. |
| 参考文献 | 1. Fuentes M E, et al. Anti-TSLPR antibody RG7258 blocks dendritic cell activation, mast cell cytokine release and reduces Th2 inflammation in a non-human primate model of allergic lung inflammation[M]//B32. ALLERGIC INFLAMMATION: MECHANISMS. American Thoracic Society, 2011: A2767-A2767. [HP521026] |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107) |
SDS-PAGE for Research Grade Anti-Human TSLPR Antibody (RG-7258)
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