Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO) (HC368016)

Name: Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO)
Brand: abinScience
SKU: HC368016
Price: 370 USD
Availability: InStock

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Número de catálogo	HC368016
Descripción	Anti-Human TYRO3/DTK/SYK Antibody (ELB031) (HC368016) is a research-grade recombinant antibody targeting RSE. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	ELB031
Sistema de expresión	Mammalian cells
Naturaleza	Recombinant
Objetivo	RSE, TYRO3, Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, BYK, Tyrosine-protein kinase BYK, DTK, TIF, Tyrosine-protein kinase DTK, SKY, Tyrosine-protein kinase SKY, Tyrosine-protein kinase receptor TYRO3
Nivel de endotoxinas	< 10 EU/mg as determined by LAL method.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q06418
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ELB031, ELB031, ELB-031
Fondo	Tyrosine-protein kinase receptor TYRO3 (DTK/SYK) is a ~96 kDa protein. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes.
Nota	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human TYRO3/DTK/SYK Antibody (ELB031)

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Datasheet

Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO) (HC368016)

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Referencias

Datasheet

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