Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO) (HC368016)

Name: Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO)
Brand: abinScience
SKU: HC368016
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
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Каталожный номер	HC368016
Описание	Anti-Human TYRO3/DTK/SYK Antibody (ELB031) (HC368016) is a research-grade recombinant antibody targeting RSE. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG
ID клона	ELB031
Система экспрессии	Mammalian cells
Характер	Recombinant
Цель	RSE, TYRO3, Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, BYK, Tyrosine-protein kinase BYK, DTK, TIF, Tyrosine-protein kinase DTK, SKY, Tyrosine-protein kinase SKY, Tyrosine-protein kinase receptor TYRO3
Уровень эндотоксинов	< 10 EU/mg as determined by LAL method.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q06418
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	ELB031, ELB031, ELB-031
Фон	Tyrosine-protein kinase receptor TYRO3 (DTK/SYK) is a ~96 kDa protein. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes.
Примечание	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human TYRO3/DTK/SYK Antibody (ELB031)

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Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO).pdf

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Anti-Human TYRO3/DTK/SYK Reference Antibody (ELB031, RUO) (HC368016)

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