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Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65533, RUO) (VK646026)

Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65533, RUO)
Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65533, RUO)
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Aperçu
Numéro de catalogueVK646026
Description
Anti-Orthohantavirus puumalaense GP Antibody (ADI-65533) (VK646026) is a research-grade recombinant antibody targeting Envelopment polyprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesOrthohantavirus puumalaense (Puumala virus) (PUUV), Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV), Seoul virus (SEOV), Dobrava-Belgrade orthohantavirus (Dobrava virus) (DOBV), Andes virus (Andes orthohantavirus), Sin Nombre orthohantavirus (SNV)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1
ID de cloneADI-65533
Système d'expression Mammalian cells
Cible Envelopment polyprotein, M polyprotein
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P41264
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Envelope glycoprotein (GP/Envelopment polyprotein) is a ~29 kDa protein. Forms homotetramers with glycoprotein N at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65533, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Orthohantavirus puumalaense GP Antibody (ADI-65533)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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