Anti-Human G-CSFR/CD114 Reference Antibody (Anumigilimab, RUO) (HV643016)

Name: Anti-Human G-CSFR/CD114 Reference Antibody (Anumigilimab, RUO)
Brand: abinScience
SKU: HV643016
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HV643016
説明	Anumigilimab (HV643016) is a research-grade recombinant antibody targeting CD114. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG4-kappa
発現システム	Mammalian cells
ターゲット	G-CSF receptor, CSF3R, GCSFR, G-CSF-R, CD114, Granulocyte colony-stimulating factor receptor
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q99062
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	CSL324, CSL-324, CSL324, G-CSFR2416593-08-1
背景	Granulocyte colony-stimulating factor receptor (CD114/CSF3R) is a ~92 kDa protein. Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
注意事項	For research use only. Not suitable for clinical or therapeutic use.

イメージ

SEC-HPLC

SEC-HPLC detection for Research Grade Anumigilimab.
Bioactivity

Detects CD114/CSF3R in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Anumigilimab
Flow CytoMetry

Flow-cytometry using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD114 monoclonal antibody (Catalog: HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry APC using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CD114 monoclonal antibody (Catalog HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry PE using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human CD114 monoclonal antibody (Catalog HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry FITC using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human CD114 monoclonal antibody (Catalog HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.