Anti-Human G-CSFR/CD114 Reference Antibody (Anumigilimab, RUO) (HV643016)

Name: Anti-Human G-CSFR/CD114 Reference Antibody (Anumigilimab, RUO)
Brand: abinScience
SKU: HV643016
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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25mg
50mg
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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	HV643016
Описание	Anumigilimab (HV643016) is a research-grade recombinant antibody targeting CD114. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG4-kappa
Система экспрессии	Mammalian cells
Цель	G-CSF receptor, CSF3R, GCSFR, G-CSF-R, CD114, Granulocyte colony-stimulating factor receptor
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q99062
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	CSL324, CSL-324, CSL324, G-CSFR2416593-08-1
Фон	Granulocyte colony-stimulating factor receptor (CD114/CSF3R) is a ~92 kDa protein. Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SEC-HPLC

SEC-HPLC detection for Research Grade Anumigilimab.
Bioactivity

Detects CD114/CSF3R in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Anumigilimab
Flow CytoMetry

Flow-cytometry using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD114 monoclonal antibody (Catalog: HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry APC using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CD114 monoclonal antibody (Catalog HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry PE using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human CD114 monoclonal antibody (Catalog HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry FITC using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human CD114 monoclonal antibody (Catalog HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.