Anti-LASV GPC Reference Antibody (Arevirumab-3, RUO) (VK453016)

Name: Anti-LASV GPC Reference Antibody (Arevirumab-3, RUO)
Brand: abinScience
SKU: VK453016
Price: 326 USD
Availability: InStock

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Numéro de catalogue	VK453016
Description	Arevirumab-3 (VK453016) is a research-grade recombinant antibody targeting GPC. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Lassa virus (LASV)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Cible	GPC
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P08669
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961
Note	For research use only. Not suitable for clinical or therapeutic use.