

| Каталожный номер | VK453016 |
|---|---|
| Описание |
Arevirumab-3 (VK453016) is a research-grade recombinant antibody targeting GPC. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Реактивность видов | Lassa virus (LASV) |
| Применения | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1-kappa |
| Система экспрессии | Mammalian cells |
| Цель | GPC |
| Уровень эндотоксинов | < 10 EU/mg |
| Чистота | >95% purity as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P08669 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Arevirumab-3.




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