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Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO) (HW651016)

Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
Свяжитесь с нами
  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHW651016
Описание
Ascrinvacumab (HW651016) is a research-grade recombinant antibody targeting Serine/threonine-protein kinase receptor R3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG2-kappa
Система экспрессии Mammalian cells
Проверенные приложения WB
Цель Serine/threonine-protein kinase receptor R3, ACVRL1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, ALK1, SKR3, TGF-B superfamily receptor type I, TSR-I
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P37023
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияPF-03446962, 1463459-96-2
Фон

Activin receptor type-1-like (ACVRL1/ALK-1) is a ~56 kDa protein. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
Изображения
  • Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Ascrinvacumab.

  • Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)

    Bioactivity

    Detects ACVRL1/ALK-1 in indirect ELISAs.

  • Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)

  • Anti-Human ALK-1 Reference Antibody (Ascrinvacumab, RUO)

    Western blot

    Western blot analysis was performed using anti-ACVRL1 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human ACVRL1 (Catalog No: HW651011)
    Lane 2: negative control

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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