Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO) (HF687196)

Name: Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO)
Brand: abinScience
SKU: HF687196
Price: 370 USD
Availability: InStock

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Especificación:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF687196

Descripción

Research Grade ascuprubart (HF687196) is a human monoclonal antibody. Suitable for Human.

Reactividad de especies

Human

Aplicaciones

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG H-gamma2-4 chimerisotype G2[11aaG4]-kappa

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P01031

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Complement C5 (ComplementC5) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways.

1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586

2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047

3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019

4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279

5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456

6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo