Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO) (HV212016)

Name: Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)
Brand: abinScience
SKU: HV212016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV212016
Description	Belimumab (HV212016) is a research-grade recombinant antibody targeting CD257. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-lambda
Système d'expression	Mammalian cells
Applications testées	WB
Cible	BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9Y275
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	LymphoStat-B, hBlySmAb-1.1, 356547-88-1
Contexte	Tumor necrosis factor ligand superfamily member 13B (CD257/BAFF) is a ~31 kDa protein. Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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Bioactivity

SEC-HPLC detection for Research Grade Belimumab.
SDS-PAGE

SDS-PAGE for Research Grade Belimumab
Western blot

Western blot analysis was performed using anti-CD257/BAFF/TNFSF13B monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD257/BAFF/TNFSF13B (Catalog No: HV212011)
Lane 2: negative control