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| カタログ番号 | HW825016 |
|---|---|
| 説明 |
Berahyaluronidase Alfa (HW825016) is a research-grade recombinant antibody targeting Hyaluronidase PH-20. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Functional assay, Research in vivo |
| クローン性 | Monoclonal |
| アイソタイプ | Human hyaluronidase isozyme-5/HYAL5 fragment engineered variant with the structural domain replaced by the corresponding region of human hyaluronidase isozyme-1/HYAL1. |
| 発現システム | Mammalian cells |
| 性質 | Recombinant |
| ターゲット | Hyaluronidase PH-20, Sperm surface protein PH-20, HYAL3, Sperm adhesion molecule 1, PH20, SPAM1, Hyal-PH20, Hyaluronoglucosaminidase PH-20 |
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Purified by Nickel column. |
| アクセッション番号 | P38567 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | 2636716-20-4 |
| 背景 | Hyaluronidase PH-20 (SPAM1) is a ~57 kDa protein. Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Berahyaluronidase Alfa
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