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| カタログ番号 | JN969016 |
|---|---|
| 説明 |
Berlimatoxumab (JN969016) is a research-grade recombinant antibody targeting lukG. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Staphylococcus aureus |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1-kappa |
| 発現システム | Mammalian cells |
| ターゲット | lukG |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | A0A6B5MC52 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | ASN-100(combinationofatidortoxumabandberlimatoxumab), ASN-2, 1939109-24-6 |
| 背景 | Berlimatoxumab (ASN-2) is an antibody. Berlimatoxumab can be used for experiment research. • Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins., PMID:24586678 • Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity., PMID:31852826 • Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies., PMID:27467113 • Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH., PMID:25371205 • Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories., PMID:35858453 • Human antibody responses against non-covalently cell wall-bound Staphylococcus aureus proteins., PMID:29459694 • Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics., PMID:20661294 • Serum neutralizing antibody after rabies postexposure prophylaxis., PMID:945973 • Pancreatic Enzyme Replacement Therapy Use in Infants With Cystic Fibrosis Diagnosed by Newborn Screening., PMID:29176494 • Vitamin E regulates mitochondrial hydrogen peroxide generation., PMID:10490278 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Berlimatoxumab.
SDS-PAGE for Research Grade Berlimatoxumab.
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