Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO) (HB202016)

Name: Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO)
Brand: abinScience
SKU: HB202016
Price: 176 USD
Availability: InStock

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概要
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概要

カタログ番号	HB202016
説明	Besilesomab (HB202016) is a research-grade recombinant antibody targeting CD67. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
発現システム	Mammalian cells
ターゲット	CD67 antigen, Carcinoembryonic antigen CGM6, Carcinoembryonic antigen-related cell adhesion molecule 8, CGM6, CD66b, Non-specific cross-reacting antigen NCA-95, CEACAM8
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P31997
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	BW250/183, 537694-98-7
背景	Cell adhesion molecule CEACAM8 (CD66b) is a ~38 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. 1. Kuroki, M. et al. (2001) Journal of leukocyte biology 70, 543-50. PMID: 11590190 2. Oikawa, S. et al. (1991) The Journal of biological chemistry 266, 7995-8001. PMID: 2022629 3. Yamanaka, T. et al. (1996) Protein expression and purification 7, 438-46. PMID: 8776764
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

イメージ

Bioactivity

Detects CD66b/CEACAM8 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Besilesomab

参考文献

データシート

Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO).pdf

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Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO) (HB202016)

概要

イメージ

参考文献

データシート

SDS

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