中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HF822016 | ||||||
|---|---|---|---|---|---|---|---|
| 説明 |
Biciromab (HF822016) is a research-grade recombinant antibody targeting FGB. Produced in mammalian cells with native-like glycosylation.
Highlights
|
||||||
| 種反応性 | Human | ||||||
| アプリケーション | ELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo | ||||||
| 宿主種 | Mouse | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG1-kappa | ||||||
| 発現システム | Mammalian cells | ||||||
| ターゲット | FGB, Fibrinogen beta chain | ||||||
| エンドトキシンレベル | < 10 EU/mg | ||||||
| 純度 | >95% purity as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | P02675 | ||||||
| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||
| 製品使用情報 |
| ||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 別名 | Indium(111In)biciromab, T2G1, 138783-13-8 | ||||||
| 背景 | Fibrinogen beta chain (FGB) is a ~55 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. | ||||||
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Biciromab.
SDS-PAGE for Research Grade Biciromab
Western blot analysis was performed using anti-FGB monoclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
