Anti-Human Fibrinogen beta chain Reference Antibody (Biciromab, RUO) (HF822016)

Name: Anti-Human Fibrinogen beta chain Reference Antibody (Biciromab, RUO)
Brand: abinScience
SKU: HF822016
Price: 176 USD
Availability: InStock

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Спецификация:

100ug
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50mg
100mg

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HF822016

Описание

Biciromab (HF822016) is a research-grade recombinant antibody targeting FGB. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Реактивность видов

Human

Применения

ELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG1-kappa

Система экспрессии

Mammalian cells

Цель

FGB, Fibrinogen beta chain

Уровень эндотоксинов

< 10 EU/mg

Чистота

>95% purity as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P02675

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

Indium(111In)biciromab, T2G1, 138783-13-8

Фон

Fibrinogen beta chain (FGB) is a ~55 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.

Примечание

For research use only. Not suitable for clinical or therapeutic use.

Изображения

Bioactivity

SEC-HPLC detection for Research Grade Biciromab.
SDS-PAGE

SDS-PAGE for Research Grade Biciromab
Western blot

Western blot analysis was performed using anti-FGB monoclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate