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Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO) (HY259056)

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Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO)
Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO)
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Vista general
Número de catálogoHY259056
Descripción
Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO) (HY259056) targeting Fibronectin. Expressed in Mammalian cells.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
ClonalidadMonoclonal
IsotiposcFv-heavy-kappa
ID de clonBifikafusp Alfa
Actividad biológica Fibronectin (FN) is a glycoprotein present in blood as well as in cells. While Fibronectin (FN) in blood has many functions, its primary role is to promote wound repair following injury [1]. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans) [2].
Sistema de expresión Mammalian cells
Naturaleza Recombinant
Objetivo Cold-insoluble globulin, CIG, FN, Fibronectin, FN1, IL2, IL-2, Aldesleukin, Interleukin-2, TCGF, T-cell growth factor
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by Nickel column.
Número de acceso P02751 & P60568
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosL19-IL-2, L19-IL2, L19IL2, 1957239-90-5
FondoBifikafusp alfa (L19-IL2) is an immunoresearch fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity.
Referencias 1. Yuan-Wan Sun, et al. Effects of E-Cigarette Aerosols with Varying Levels of Nicotine on Biomarkers of Oxidative Stress and Inflammation in Mice. Chem Res Toxicol. 2021 Apr 19;34(4):1161-1168. [HY259056]
2. Roumen Pankov, et al. Fibronectin at a glance. J Cell Sci. 2002 Oct 15;115(Pt 20):3861-3. [HY259056]
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Bifikafusp Alfa

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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