Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO) (HY259056)

Name: Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO)
Brand: abinScience
SKU: HY259056
Price: 400 USD
Availability: InStock

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Numéro de catalogue	HY259056
Description	Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO) (HY259056) targeting Fibronectin. Expressed in Mammalian cells.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Clonalité	Monoclonal
Isotype	scFv-heavy-kappa
ID de clone	Bifikafusp Alfa
Activité biologique	Fibronectin (FN) is a glycoprotein present in blood as well as in cells. While Fibronectin (FN) in blood has many functions, its primary role is to promote wound repair following injury [1]. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans) [2].
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	Cold-insoluble globulin, CIG, FN, Fibronectin, FN1, IL2, IL-2, Aldesleukin, Interleukin-2, TCGF, T-cell growth factor
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Purified by Nickel column.
Numéro d'accès	P02751 & P60568
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	L19-IL-2, L19-IL2, L19IL2, 1957239-90-5
Contexte	Bifikafusp alfa (L19-IL2) is an immunoresearch fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity.
Reférences	1. Yuan-Wan Sun, et al. Effects of E-Cigarette Aerosols with Varying Levels of Nicotine on Biomarkers of Oxidative Stress and Inflammation in Mice. Chem Res Toxicol. 2021 Apr 19;34(4):1161-1168. [HY259056] 2. Roumen Pankov, et al. Fibronectin at a glance. J Cell Sci. 2002 Oct 15;115(Pt 20):3861-3. [HY259056]
Note	For research use only. Not suitable for clinical or therapeutic use.

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Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO).pdf

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Anti-Human Fibronectin & IL-2 Bispecific Reference Antibody (Bifikafusp Alfa, RUO) (HY259056)

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