

| Numéro de catalogue | CY257016 | ||||
|---|---|---|---|---|---|
| Description |
Blontuvetmab (CY257016) is a research-grade recombinant antibody targeting CD20. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Reactivité des espèces | Canine | ||||
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo | ||||
| Espèce hôte | Canine | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG2-kappa-lambda | ||||
| Cible | B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, CD20, Leukocyte surface antigen Leu-16, MS4A1, Membrane-spanning 4-domains subfamily A member 1 | ||||
| Niveau d'endotoxines | < 10 EU/mg | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q3C2E2 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Noms alternatifs | AT-004, VT-007, 1608112-78-2 | ||||
| Contexte | B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva). | ||||
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Blontuvetmab.
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