Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO) (HY255016)

Name: Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO)
Brand: abinScience
SKU: HY255016
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HY255016
Description	Caplacizumab (HY255016) is a research-grade recombinant antibody targeting von Willebrand antigen II. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	VH-VH
Système d'expression	Mammalian cells
Cible	von Willebrand antigen II, von Willebrand factor, F8VWF, vWF, VWF
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P04275
Forme	Liquid
Tampon de stockage	20 mM citric acid, 6.2% sucrose, 0.01% Tween80 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ALX-0081, PMP12A2h1-linkerAAA-PMP12A2h1, caplacizumab-yhdp, 915810-67-2
Contexte	von Willebrand factor (VWF) is a ~309 kDa protein. Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Note	For research use only. Not suitable for clinical or therapeutic use.