Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO) (HY255016)

Name: Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO)
Brand: abinScience
SKU: HY255016
Price: 176 USD
Availability: InStock

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概要

カタログ番号	HY255016
説明	Caplacizumab (HY255016) is a research-grade recombinant antibody targeting von Willebrand antigen II. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	VH-VH
発現システム	Mammalian cells
ターゲット	von Willebrand antigen II, von Willebrand factor, F8VWF, vWF, VWF
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P04275
形態	Liquid
保存バッファー	20 mM citric acid, 6.2% sucrose, 0.01% Tween80 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	ALX-0081, PMP12A2h1-linkerAAA-PMP12A2h1, caplacizumab-yhdp, 915810-67-2
背景	von Willebrand factor (VWF) is a ~309 kDa protein. Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
注意事項	For research use only. Not suitable for clinical or therapeutic use.