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Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO) (HC669036)

Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)
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  • 概要

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概要
カタログ番号HC669036
説明
Capromab (HC669036) is a research-grade recombinant antibody targeting NAALAD1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG1-kappa
発現システム Mammalian cells
テスト済みアプリケーション FCM
ターゲット NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q04609
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名7E11-C5.3radiolabelled, IndiumIn1111ProstaScint, capromabpendetide, 145464-28-4
背景

Glutamate carboxypeptidase 2 (FOLH1/PSMA) is a ~84 kDa protein. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
イメージ
  • Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Capromab.

  • Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)

    Flow CytoMetry

    Flow-cytometry using APC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human FOLH1 monoclonal antibody (Catalog: HC669036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)

    Flow CytoMetry

    Flow-cytometry using FITC anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human FOLH1 monoclonal antibody (Catalog: HC669036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)

    Flow CytoMetry

    Flow-cytometry using PE anti-human FOLH1 antibody. LNCAP cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human FOLH1 monoclonal antibody (Catalog: HC669036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human FOLH1/PSMA Reference Antibody (Capromab, RUO)

    Flow CytoMetry

    Flow-cytometry using anti-human FOLH1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human FOLH1 monoclonal antibody (Catalog: HC669036) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
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