Anti-Human EpCAM/TROP1 & CD3 epsilon Bispecific Reference Antibody (Catumaxomab, RUO) (HB104066)

Name: Anti-Human EpCAM/TROP1 & CD3 epsilon Bispecific Reference Antibody (Catumaxomab, RUO)
Brand: abinScience
SKU: HB104066
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB104066
Description	Catumaxomab (HB104066) is a research-grade recombinant antibody targeting CD326. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	MouseHybridRat
Clonalité	Monoclonal
Isotype	IgG2a-kappa/IgG2b-lambda
Cible	Adenocarcinoma-associated antigen, CD326, Cell surface glycoprotein Trop-1, EGP, EGP314, EPCAM, Ep-CAM, Epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, GA733-2, KS 1/4 antigen, KSA, M1S2, M4S1, MIC18, Major gastrointestinal tumor-associated protein GA733-2, TACSTD1, TROP1, Tumor-associated calcium signal transducer 1, hEGP314, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P16422 & P07766
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Bispecific, MusmusG2akappa, anti-EPCAM(Ho-3/TP-A-01)/Ratsp.G2blambda, anti-CD3E(26/II/6-1.2), TPBs01, 509077-98-9
Contexte	Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Catumaxomab

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Anti-Human EpCAM/TROP1 & CD3 epsilon Bispecific Reference Antibody (Catumaxomab, RUO).pdf

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