Anti-Human CD307e/FCRL5 & CD3 epsilon Bispecific Reference Antibody (Cevostamab, RUO) (HV698016)

Name: Anti-Human CD307e/FCRL5 & CD3 epsilon Bispecific Reference Antibody (Cevostamab, RUO)
Brand: abinScience
SKU: HV698016
Price: 176 USD
Availability: InStock

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Спецификация:

100ug
1mg
5mg
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Обзор

Каталожный номер	HV698016
Описание	Cevostamab (HV698016) is a research-grade recombinant antibody targeting CD307. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-kappa
Система экспрессии	Mammalian cells
Цель	FcRL5, FCRH5, FCRL5, Fc receptor homolog 5, FcRH5, CD307e, FcR-like protein 5, IRTA2, Immune receptor translocation-associated protein 2, BXMAS1, Fc receptor-like protein 5, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q96RD9 & P07766
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Bispecific, BFCR-4350-A, BFCR-4350A, RG-6160, RO-7187797, 2249888-53-5
Фон	Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based BsAb that targets membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells as well as CD3 on T cells. Moreover, Cevostamab facilitates efficient synapse formation, improves killing activity of T cells against MM tumor cells.
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Cevostamab.
Bioactivity

SEC-HPLC detection for Research Grade Cevostamab.

Ссылки

Даташит

Anti-Human CD307e/FCRL5 & CD3 epsilon Bispecific Reference Antibody (Cevostamab, RUO).pdf

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Formula

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