

| Numéro de catalogue | HF998056 |
|---|---|
| Description |
Research Grade Clenoliximab (HF998056) is a chimeric monoclonal antibody detecting T-cell surface antigen T4/Leu-3 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
|
| Reactivité des espèces | Human |
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Espèce hôte | Chimeric |
| Clonalité | Monoclonal |
| Isotype | IgG4-lambda |
| Cible | CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
| Niveau d'endotoxines | < 10 EU/mg |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P01730 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CE9, 4PE, IDEC-151, 182912-58-9 |
| Contexte | T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4,CD4) is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P), Lambda Recombinant Isotype Control Antibody (HyHEL-10) (HV799023) |

SDS-PAGE for Research Grade Clenoliximab.




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