Anti-Human PTK7/CCK-4 Reference Antibody (Cofetuzumab, RUO) (HC437016)

Name: Anti-Human PTK7/CCK-4 Reference Antibody (Cofetuzumab, RUO)
Brand: abinScience
SKU: HC437016
Price: 176 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue	HC437016
Description	Cofetuzumab (HC437016) is a research-grade recombinant antibody targeting Protein-tyrosine kinase 7. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Cible	Protein-tyrosine kinase 7, Inactive tyrosine-protein kinase 7, CCK4, PTK7, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7, CCK-4, Pseudo tyrosine kinase receptor 7
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q13308
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	PF-06523435, hu24, Anti-PTK7ADC, PF-06647020, PTK7-ADC, 1869928-62-0
Contexte	Inactive tyrosine-protein kinase 7 (PTK7/CCK-4) is a ~118 kDa protein. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

Images

Bioactivity

Detects Human PTK7/CCK-4 in indirect ELISAs.
Bioactivity

SEC-HPLC detection for Research Grade Cofetuzumab.
SDS-PAGE

SDS-PAGE for Research Grade Cofetuzumab.

Reférences

Fiche technique

Anti-Human PTK7/CCK-4 Reference Antibody (Cofetuzumab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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