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| カタログ番号 | HB849016 |
|---|---|
| 説明 |
Corifollitropin alfa (HB849016) is a research-grade recombinant antibody targeting Follitropin receptor. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | Fusion - Follicle-stimulating hormone (FSH) - CTP (C-terminal peptide of the β-subunit of human chorionic gonadotropin (hCG)) |
| 発現システム | Mammalian cells |
| ターゲット | Follitropin receptor, LGR1, Follicle-stimulating hormone receptor, FSHR, FSH-R |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Purified by Nickel column. |
| アクセッション番号 | P23945 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | FSH-CTPfusion, Org36286, corifollitropin-alpha |
| 背景 | Follicle-stimulating hormone receptor (FSHR) is a ~78 kDa protein. G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. 1. Costagliola, S. et al. (2002) The EMBO journal 21, 504-13. PMID: 11847099 2. Uchida, S. et al. (2013) PloS one 8, e75478. PMID: 24058690 3. Jiang, X. et al. (2014) The Journal of biological chemistry 289, 14273-82. PMID: 24692546 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Corifollitropin alfa
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