Anti-Human TROP-2 Reference Antibody (Datopotamab, RUO) (HY373026)

Name: Anti-Human TROP-2 Reference Antibody (Datopotamab, RUO)
Brand: abinScience
SKU: HY373026
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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SDS

Vista general

Número de catálogo	HY373026
Descripción	Datopotamab (HY373026) is a research-grade recombinant antibody targeting Pancreatic carcinoma marker protein GA733-1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
Sistema de expresión	Mammalian cells
Aplicaciones probadas	WB, FCM
Objetivo	Pancreatic carcinoma marker protein GA733-1, Tumor-associated calcium signal transducer 2, M1S1, TROP2, TACSTD2, Cell surface glycoprotein Trop-2, GA733-1, Membrane component chromosome 1 surface marker 1
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P09758
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	DS-1062, DS-1062a, Datopotamabderuxtecan, 2267989-53-5
Fondo	Tumor-associated calcium signal transducer 2 (TACSTD2/TROP2) is a ~35 kDa protein. May function as a growth factor receptor. TACSTD2 is the therapeutic target of sacituzumab govitecan (Trodelvy).
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Bioactivity

Detects Human TROP2 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Datopotamab.
Flow CytoMetry

Flow-cytometry using anti-human TACSTD2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human TACSTD2 monoclonal antibody (Catalog: HY373026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-TACSTD2/TROP2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human TACSTD2/TROP2 (Catalog No: HY373011)
Flow cytometry

Flow-cytometry using FITC anti-human TACSTD2 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human TACSTD2 monoclonal antibody (Catalog HY373026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using FITC anti-human TACSTD2 antibody. MCF7 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human TACSTD2 monoclonal antibody (Catalog HY373026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.