Anti-Human TROP-2 Reference Antibody (Datopotamab, RUO) (HY373026)

Name: Anti-Human TROP-2 Reference Antibody (Datopotamab, RUO)
Brand: abinScience
SKU: HY373026
Price: 176 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HY373026
説明	Datopotamab (HY373026) is a research-grade recombinant antibody targeting Pancreatic carcinoma marker protein GA733-1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
発現システム	Mammalian cells
テスト済みアプリケーション	WB, FCM
ターゲット	Pancreatic carcinoma marker protein GA733-1, Tumor-associated calcium signal transducer 2, M1S1, TROP2, TACSTD2, Cell surface glycoprotein Trop-2, GA733-1, Membrane component chromosome 1 surface marker 1
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P09758
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	DS-1062, DS-1062a, Datopotamabderuxtecan, 2267989-53-5
背景	Tumor-associated calcium signal transducer 2 (TACSTD2/TROP2) is a ~35 kDa protein. May function as a growth factor receptor. TACSTD2 is the therapeutic target of sacituzumab govitecan (Trodelvy).
注意事項	For research use only. Not suitable for clinical or therapeutic use.

イメージ

Bioactivity

Detects Human TROP2 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Datopotamab.
Flow CytoMetry

Flow-cytometry using anti-human TACSTD2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human TACSTD2 monoclonal antibody (Catalog: HY373026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-TACSTD2/TROP2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human TACSTD2/TROP2 (Catalog No: HY373011)
Flow cytometry

Flow-cytometry using FITC anti-human TACSTD2 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human TACSTD2 monoclonal antibody (Catalog HY373026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using FITC anti-human TACSTD2 antibody. MCF7 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human TACSTD2 monoclonal antibody (Catalog HY373026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.