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Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO) (HV615016)

Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO)
Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

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  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHV615016
Описание
denrakibart (HV615016) is a research-grade recombinant antibody targeting CCL17/TARC.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG2, Kappa
Виды Human
Цель CCL17/TARC
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Номер доступа Q92583
Форма Liquid
Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия2922866-66-6
Фон

C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Imai, T. et al. (1996) The Journal of biological chemistry 271, 21514-21. PMID: 8702936
2. Imai, T. et al. (1997) The Journal of biological chemistry 272, 15036-42. PMID: 9169480
3. Garlisi, CG. et al. (1999) European journal of immunology 29, 3210-5. PMID: 10540332
4. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade denrakibart

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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