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Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Diridavumab, RUO) (VK515016)

Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Diridavumab, RUO)
Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Diridavumab, RUO)
Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Diridavumab, RUO)
Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Diridavumab, RUO)
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Aperçu
Numéro de catalogueVK515016
Description
Diridavumab (VK515016) is a research-grade recombinant antibody targeting HA/Hemagglutinin. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesInfluenza A virus (H1, H2, H5, H6, H8, H9 subtype)
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, lambda
Cible HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès CAS: 1393659-46-5
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsCR-6261, CR6261, 1393659-46-5
Contexte

Hemagglutinin (HA) is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Diridavumab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Diridavumab.

  • Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (Diridavumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Diridavumab.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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