Anti-Ganglioside GD3 Reference Antibody (Ecromeximab, RUO) (YP464016)

Name: Anti-Ganglioside GD3 Reference Antibody (Ecromeximab, RUO)
Brand: abinScience
SKU: YP464016
Price: 176 USD
Availability: InStock

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Обзор

Каталожный номер	YP464016
Описание	Ecromeximab (YP464016) is a research-grade recombinant antibody targeting Ganglioside GD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	General
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Chimeric
Клоональность	Monoclonal
Изотип	IgG1-kappa
Система экспрессии	Mammalian cells
Цель	Ganglioside GD3
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	PubChem CID: 20057323
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	KM871, KW-2871, CAS: 292819-64-8
Фон	Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma. • GD3 ganglioside and apoptosis., PMID:12531552 • Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474 • Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197 • A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669 • Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994 • Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773 • Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804 • Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478 • Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859 • Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

Bioactivity

SEC-HPLC detection for Research Grade Ecromeximab.
SDS-PAGE

SDS-PAGE for Research Grade Ecromeximab.

Ссылки

Даташит

Anti-Ganglioside GD3 Reference Antibody (Ecromeximab, RUO).pdf

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