

| Каталожный номер | HA532016 |
|---|---|
| Описание |
efgitasialase alfa (HA532016) is a research-grade recombinant antibody targeting sialidase-2.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, Functional assay, Research in vivo |
| Клоональность | Monoclonal |
| Система экспрессии | Mammalian cells |
| Характер | Recombinant |
| Цель | sialidase-2 |
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. |
| Чистота | >95% as determined by SDS-PAGE. |
| Номер доступа | Q9Y3R4 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | 2891502-37-5 |
| Фон | Sialidase-2 is a ~42 kDa protein. Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Recognizes sialyl linkage positions of the glycan moiety as well as the supramolecular organization of the sialoglycoconjugate. Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles. Hydrolyzes monomeric GM1 ganglioside, but has no activity toward the miscellar form. Has lower sialidase activity for glycoproteins such as fetuin and TF/transferrin that carry a mixture of alpha-(2->3) and alpha-(2->6)-sialyl linkages. 1. Tringali, C. et al. (2004) The Journal of biological chemistry 279, 3169-79. PMID: 14613940 2. Mozzi, A. et al. (2012) Proteins 80, 1123-32. PMID: 22228546 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |
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