

| Numéro de catalogue | HC100016 |
|---|---|
| Description |
eflumenibep alfa (HC100016) is a research-grade recombinant antibody targeting SPINK2.
Highlights
|
| Reactivité des espèces | Human |
| Applications | Functional assay |
| Clonalité | Monoclonal |
| Isotype | SPINK2-Fc |
| Système d'expression | Mammalian cells |
| Nature | Recombinant |
| Cible | SPINK2 |
| Niveau d'endotoxines | < 10 EU/mg as determined by LAL method. |
| Pureté | >95% as determined by SDS-PAGE. |
| Numéro d'accès | P20155 |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CAS: 2418159-10-9 |
| Contexte | Serine protease inhibitor Kazal-type 2 is a ~9 kDa protein. As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects. May be involved in the regulation of serine protease-dependent germ cell apoptosis. It also inhibits trypsin. 1. Kherraf, ZE. et al. (2017) EMBO molecular medicine 9, 1132-1149. PMID: 28554943 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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