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Anti-Human CD39/ENTPD1 Reference Antibody (Eltivutabart, RUO) (HW564096)

Anti-Human CD39/ENTPD1 Reference Antibody (Eltivutabart, RUO)
Anti-Human CD39/ENTPD1 Reference Antibody (Eltivutabart, RUO)
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Aperçu
Numéro de catalogueHW564096
Description
eltivutabart (HW564096) is a research-grade recombinant antibody targeting CD39.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG4, Kappa
Espèces Human
Cible CD39/ENTPD1
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Numéro d'accès P49961
Forme Liquid
Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs2935496-38-9
Contexte

Ectonucleoside triphosphate diphosphohydrolase 1 (CD39/ENTPD1) is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.

1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 8529670
2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624
3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 8955160
4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251
Note For research use only. Not suitable for clinical or therapeutic use.
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Images
  • Anti-Human CD39/ENTPD1 Reference Antibody (Eltivutabart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade eltivutabart

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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