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Anti-Human F10/Factor X & F9/Factor IX Bispecific Reference Antibody (Emicizumab, RUO) (HF610016)

Anti-Human F10/Factor X & F9/Factor IX Bispecific Reference Antibody (Emicizumab, RUO)
Anti-Human F10/Factor X & F9/Factor IX Bispecific Reference Antibody (Emicizumab, RUO)
Anti-Human F10/Factor X & F9/Factor IX Bispecific Reference Antibody (Emicizumab, RUO)
Anti-Human F10/Factor X & F9/Factor IX Bispecific Reference Antibody (Emicizumab, RUO)
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  • 1mg
  • 5mg
  • 10mg
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  • 概要

  • イメージ

  • 参考文献

  • データシート

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概要
カタログ番号HF610016
説明
Emicizumab (HF610016) is a research-grade recombinant antibody targeting Stuart factor. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG4-kappa
発現システム Mammalian cells
ターゲット Stuart factor, Stuart-Prower factor, Coagulation factor X, F10, Plasma thromboplastin component, F9, Christmas factor, Coagulation factor IX, PTC
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 CAS: 1610943-06-0
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名Bispecific, ACE-910, RG6013, hBS910, 1610943-06-0
背景Denecimig (Mim8) is a novel activated coagulation factor VIII-mimetic human bispecific antibody with anti-FIXa and anti-FX arms that potently stimulates FX activation resulting in efficacious haemostasis in vitro and in vivo.
注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
イメージ
  • Anti-Human F10/Factor X & F9/Factor IX Bispecific Reference Antibody (Emicizumab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Emicizumab.

  • Anti-Human F10/Factor X & F9/Factor IX Bispecific Reference Antibody (Emicizumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Emicizumab

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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