Anti-Human Complement C2 Reference Antibody (Empasiprubart, RUO) (HY106016)

Name: Anti-Human Complement C2 Reference Antibody (Empasiprubart, RUO)
Brand: abinScience
SKU: HY106016
Price: 176 USD
Availability: InStock

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Спецификация:

100ug
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50mg
100mg

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Каталожный номер	HY106016
Описание	Empasiprubart (HY106016) is a research-grade recombinant antibody targeting Complement C2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1, kappa
Система экспрессии	Mammalian cells
Характер	Recombinant
Цель	Complement C2, C2, C3/C5 convertase
Уровень эндотоксинов	< 10 EU/mg as determined by LAL method.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P06681
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	2579031-19-7
Фон	Complement C2 is a ~83 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Milder, FJ. et al. (2006) Structure (London, England : 1993) 14, 1587-97. PMID: 17027507 3. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 4. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 5. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 6. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Empasiprubart

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Даташит

Anti-Human Complement C2 Reference Antibody (Empasiprubart, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Наборы для анализа

Anti-Human Complement C2 Reference Antibody (Empasiprubart, RUO) (HY106016)

Обзор

Изображения

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SDS