Anti-Human TNF RII/TNFRSF1B Reference Antibody (Emunkitug, RUO) (HB070066)

Name: Anti-Human TNF RII/TNFRSF1B Reference Antibody (Emunkitug, RUO)
Brand: abinScience
SKU: HB070066
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HB070066
Description	emunkitug (HB070066) is a research-grade recombinant antibody targeting CD120. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1, Kappa
Espèces	Human
Cible	CD120b/TNFRSF1B/TNFR2
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Numéro d'accès	P20333
Forme	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	2916519-48-5
Contexte	Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFRSF1B) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity.
Note	For research use only. Not suitable for clinical or therapeutic use.