Anti-Human MUC5AC Reference Antibody (Ensituximab, RUO) (HX246016)

Name: Anti-Human MUC5AC Reference Antibody (Ensituximab, RUO)
Brand: abinScience
SKU: HX246016
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HX246016
Description	Ensituximab (HX246016) is a research-grade recombinant antibody targeting Mucin-5 subtype AC. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Chimeric
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Cible	Mucin-5 subtype AC, tracheobronchial, Gastric mucin, Mucin-5AC, TBM, MUC-5AC, Tracheobronchial mucin, Major airway glycoprotein, MUC5AC, MUC5
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P98088
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	NOE-102, NPC-1C, 1092658-06-4
Contexte	Mucin-5AC (MUC5AC) is a ~585 kDa protein. Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD). 1. Van de Bovenkamp, JH. et al. (2003) Helicobacter 8, 521-32. PMID: 14535999 2. Perez-Vilar, J. et al. (2004) Glycobiology 14, 325-37. PMID: 14718370
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)