Anti-Human MUC5AC Reference Antibody (Ensituximab, RUO) (HX246016)

Name: Anti-Human MUC5AC Reference Antibody (Ensituximab, RUO)
Brand: abinScience
SKU: HX246016
Price: 176 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HX246016
説明	Ensituximab (HX246016) is a research-grade recombinant antibody targeting Mucin-5 subtype AC. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Chimeric
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
発現システム	Mammalian cells
ターゲット	Mucin-5 subtype AC, tracheobronchial, Gastric mucin, Mucin-5AC, TBM, MUC-5AC, Tracheobronchial mucin, Major airway glycoprotein, MUC5AC, MUC5
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P98088
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	NOE-102, NPC-1C, 1092658-06-4
背景	Mucin-5AC (MUC5AC) is a ~585 kDa protein. Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD). 1. Van de Bovenkamp, JH. et al. (2003) Helicobacter 8, 521-32. PMID: 14535999 2. Perez-Vilar, J. et al. (2004) Glycobiology 14, 325-37. PMID: 14718370
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)