Anti-Human αVβ3 Reference Antibody (Etaracizumab, RUO) (HY065026)

Name: Anti-Human αVβ3 Reference Antibody (Etaracizumab, RUO)
Brand: abinScience
SKU: HY065026
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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SDS

Vista general

Número de catálogo	HY065026
Descripción	Etaracizumab (HY065026) is a research-grade recombinant antibody targeting CD51. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-nd
Sistema de expresión	Mammalian cells
Aplicaciones probadas	FCM
Objetivo	MSK8, VNRA, Vitronectin receptor, Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, ITGAV, VTNR, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P06756 & P05106
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	MEDI-522, hLM60, 892553-42-3
Fondo	Etaracizumab (LM 609) is an αvβ3 integrin IgG1 monoclonal antibody. Etaracizumab inhibits angiogenesis and melanoma tumor growth. Etaracizumab can be used to research anticancer.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human Integrin alpha V/CD51 Reference Antibody (Etaracizumab, RUO)
Flow CytoMetry

Flow-cytometry using APC anti-human CD51&CD61 antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD51&CD61 monoclonal antibody (Catalog: HY065026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human CD51&CD61 antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD51&CD61 monoclonal antibody (Catalog: HY065026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.