Anti-Human αVβ3 Reference Antibody (Etaracizumab, RUO) (HY065026)

Name: Anti-Human αVβ3 Reference Antibody (Etaracizumab, RUO)
Brand: abinScience
SKU: HY065026
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HY065026
Description	Etaracizumab (HY065026) is a research-grade recombinant antibody targeting CD51. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-nd
Système d'expression	Mammalian cells
Applications testées	FCM
Cible	MSK8, VNRA, Vitronectin receptor, Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, ITGAV, VTNR, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P06756 & P05106
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	MEDI-522, hLM60, 892553-42-3
Contexte	Etaracizumab (LM 609) is an αvβ3 integrin IgG1 monoclonal antibody. Etaracizumab inhibits angiogenesis and melanoma tumor growth. Etaracizumab can be used to research anticancer.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE

SDS-PAGE for Anti-Human Integrin alpha V/CD51 Reference Antibody (Etaracizumab, RUO)
Flow CytoMetry

Flow-cytometry using APC anti-human CD51&CD61 antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD51&CD61 monoclonal antibody (Catalog: HY065026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human CD51&CD61 antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD51&CD61 monoclonal antibody (Catalog: HY065026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.