Anti-Human αVβ3 Reference Antibody (Etaracizumab, RUO) (HY065026)

Name: Anti-Human αVβ3 Reference Antibody (Etaracizumab, RUO)
Brand: abinScience
SKU: HY065026
Price: 176 USD
Availability: InStock

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100ug
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Изображения
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Даташит
SDS

Обзор

Каталожный номер	HY065026
Описание	Etaracizumab (HY065026) is a research-grade recombinant antibody targeting CD51. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-nd
Система экспрессии	Mammalian cells
Проверенные приложения	FCM
Цель	MSK8, VNRA, Vitronectin receptor, Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, ITGAV, VTNR, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P06756 & P05106
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	MEDI-522, hLM60, 892553-42-3
Фон	Etaracizumab (LM 609) is an αvβ3 integrin IgG1 monoclonal antibody. Etaracizumab inhibits angiogenesis and melanoma tumor growth. Etaracizumab can be used to research anticancer.
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human Integrin alpha V/CD51 Reference Antibody (Etaracizumab, RUO)
Flow CytoMetry

Flow-cytometry using APC anti-human CD51&CD61 antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD51&CD61 monoclonal antibody (Catalog: HY065026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human CD51&CD61 antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD51&CD61 monoclonal antibody (Catalog: HY065026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.