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Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO) (VK539026)

Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)
Precio(USD):
Especificación:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Número:
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Vista general
Número de catálogoVK539026
Descripción
Exbivirumab (VK539026) is a research-grade recombinant antibody targeting Large envelope protein. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHepatitis B virus (HBV)
AplicacionesELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, lambda
Sistema de expresión Mammalian cells
Objetivo Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S
Nivel de endotoxinas < 10 EU/mg
Pureza >95% purity as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P03142
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos19.79.5, HepeX-B(combinationofexbivirumabandlibivirumab), 569658-80-6
Fondo

Large envelope protein (HBsAg) is a ~42 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane.

Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Exbivirumab.

  • Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)

    Bioactivity

    Detects S/L-HBsAg/L glycoprotein in indirect ELISAs.

  • Anti-HBV HBsAg Reference Antibody (Exbivirumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Exbivirumab

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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