

| Número de catálogo | VK515026 | ||||
|---|---|---|---|---|---|
| Descripción |
Firivumab (VK515026) is a research-grade recombinant antibody targeting HA/Hemagglutinin. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Reactividad de especies | Influenza A virus (H1, H2, H5, H9 subtype) | ||||
| Aplicaciones | ELISA, Bioactivity: FCM, Functional assay, Research in vivo | ||||
| Especie huésped | Human | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1, kappa | ||||
| Objetivo | HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | ||||
| Nivel de endotoxinas | < 10 EU/mg | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | CAS: 1443004-15-6 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Nombres alternativos | CT-P22, 1443004-15-6 | ||||
| Fondo | Hemagglutinin (HA) is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. | ||||
| Nota | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Firivumab.
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