Anti-Human MUC-1 Reference Antibody (Gatipotuzumab, RUO) (HB102016)

Name: Anti-Human MUC-1 Reference Antibody (Gatipotuzumab, RUO)
Brand: abinScience
SKU: HB102016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB102016
Description	Gatipotuzumab (HB102016) is a research-grade recombinant antibody targeting CD227. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
Applications testées	FCM
Cible	Breast carcinoma-associated antigen DF3, CA 15-3, CD227, Cancer antigen 15-3, Carcinoma-associated mucin, EMA, Episialin, H23AG, KL-6, Krebs von den Lungen-6, MUC-1, MUC1, MUC1-CT, MUC1-NT, MUC1-alpha, MUC1-beta, Mucin-1, Mucin-1 subunit alpha, Mucin-1 subunit beta, PEM, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P15941
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	PankoMab, PankoMab-GEX, hPankoMab, 1264737-26-9
Contexte	Mucin-1 (CD227/MUC1) is a ~122 kDa protein. The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10) (HV080407) Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

SDS-PAGE

SDS-PAGE for Research Grade Gatipotuzumab.
Flow CytoMetry

Flow-cytometry using APC anti-human CD227 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD227 monoclonal antibody (Catalog: HB102016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using FITC anti-human CD227 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD227 monoclonal antibody (Catalog: HB102016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human CD227 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD227 monoclonal antibody (Catalog: HB102016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.