



| Número de catálogo | VK515046 | ||||
|---|---|---|---|---|---|
| Descripción |
Gedivumab (VK515046) is a research-grade recombinant antibody targeting HA/Hemagglutinin. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Reactividad de especies | Influenza A virus (H1, H2, H3, H5, H7 subtype) | ||||
| Aplicaciones | ELISA, Bioactivity: FCM, Functional assay, Research in vivo | ||||
| Especie huésped | Human | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1, kappa | ||||
| Objetivo | HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | ||||
| Nivel de endotoxinas | < 10 EU/mg | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | CAS: 1807954-17-1 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Nombres alternativos | MHAA4549A, RO6876802, RG7745, 1807954-17-1 | ||||
| Fondo | Hemagglutinin (HA) is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. | ||||
| Nota | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Gedivumab.

SDS-PAGE for Research Grade Gedivumab.
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