Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO) (HS840016)

Name: Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)
Brand: abinScience
SKU: HS840016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HS840016
Description	Girentuximab (HS840016) is a research-grade recombinant antibody targeting Membrane antigen MN. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Chimeric
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Applications testées	FCM
Cible	Membrane antigen MN, P54/58N, Carbonic anhydrase 9, Renal cell carcinoma-associated antigen G250, CA-IX, CAIX, pMW1, Carbonic anhydrase IX, RCC-associated antigen G250, Carbonate dehydratase IX, CA9, MN, G250
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q16790
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	WX-G250, cG250, 916138-87-9
Contexte	Carbonic anhydrase 9 (CA9) is a ~49 kDa protein. Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Girentuximab.
SDS-PAGE

SDS-PAGE for Anti-Human CA9 Reference Antibody (Girentuximab, RUO)
Flow CytoMetry

Flow-cytometry using anti-human CA9 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CA9 monoclonal antibody (Catalog: HS840016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.