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Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO) (HS840016)

Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)
Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)
Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)
Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)
Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)
Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)
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  • 概要

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概要
カタログ番号HS840016
説明
Girentuximab (HS840016) is a research-grade recombinant antibody targeting Membrane antigen MN. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Chimeric
クローン性Monoclonal
アイソタイプIgG1-kappa
発現システム Mammalian cells
テスト済みアプリケーション FCM
ターゲット Membrane antigen MN, P54/58N, Carbonic anhydrase 9, Renal cell carcinoma-associated antigen G250, CA-IX, CAIX, pMW1, Carbonic anhydrase IX, RCC-associated antigen G250, Carbonate dehydratase IX, CA9, MN, G250
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q16790
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名WX-G250, cG250, 916138-87-9
背景

Carbonic anhydrase 9 (CA9) is a ~49 kDa protein. Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).

注意事項 For research use only. Not suitable for clinical or therapeutic use.
イメージ
  • Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Girentuximab.

  • Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human CA9 Reference Antibody (Girentuximab, RUO)

  • Anti-Human Carbonic Anhydrase IX/CA9 Reference Antibody (Girentuximab, RUO)

    Flow CytoMetry

    Flow-cytometry using anti-human CA9 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CA9 monoclonal antibody (Catalog: HS840016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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V₁ (Stock Vol.)
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Working Solution
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