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Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO) (HX126026)

Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHX126026
Описание
Gresonitamab (HX126026) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
Изотип(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
Проверенные приложения FCM
Цель CLDN18.2, Claudin-18.2, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P56856-2 & P07766
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияBispecific, AMG910, AMG-910, AMG9102413817-97-5
ФонGresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma.
Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Изображения
  • Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Gresonitamab

  • Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)

    Flow cytometry

    Flow-cytometry APC using anti-human CLDN18.2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CLDN18.2 monoclonal antibody (Catalog HX126026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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